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HelpTest Code BMAMA Basic Metabolic Panel, Serum
Shipping Instructions
Necessary Information
Patient's age and sex are required.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.
Useful For
Routine health monitoring or patient monitoring while hospitalized for information regarding metabolism, including the current kidney status, electrolyte, and acid/base balance, and blood glucose
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| KS | Potassium, S | Yes | Yes |
| NAS | Sodium, S | Yes | Yes |
| CL | Chloride, S | Yes | Yes |
| HCO3 | Bicarbonate, S | Yes | Yes |
| AGAP | Anion Gap | No | Yes |
| BUN | Bld Urea Nitrog (BUN), S | Yes | Yes |
| CRTS1 | Creatinine with eGFR, S | Yes | Yes |
| CA | Calcium, Total, S | Yes | Yes |
| GLURA | Glucose, Random, S | Yes | Yes |
Method Name
KS, NAS, CL: Potentiometric, Indirect Ion-Selective Electrode
HCO3: Photometric/Enzymatic
AGAP: Calculation
BUN: Photometric, Urease
CRTS1: Enzymatic Colorimetric Assay
CA: Photometric
GLURA: Enzymatic Photometric Assay
Reporting Name
Basic Metabolic Panel, SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated | 24 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Clinical Information
The basic metabolic panel measures 8 analytes and calculates an anion gap. It is used to assess kidney status, electrolyte, and acid/base balance, and blood glucose.
Reference Values
SODIUM
<1 year: Not established
≥1 year: 135-145 mmol/L
POTASSIUM
<1 year: Not established
≥1 year: 3.6-5.2 mmol/L
CHLORIDE
<1 year: Not established
1-17 years: 102-112 mmol/L
≥18 years: 98-107 mmol/L
BICARBONATE
Males:
<1 year: Not established
1-2 years: 17-25 mmol/L
3 years: 18-26 mmol/L
4-5 years: 19-27 mmol/L
6-7 years: 20-28 mmol/L
8-17 years: 21-29 mmol/L
≥18 years: 22-29 mmol/L
Females:
<1 year: Not established
1-3 years: 18-25 mmol/L
4-5 years: 19-26 mmol/L
6-7 years: 20-27 mmol/L
8-9 years: 21-28 mmol/L
≥10 years: 22-29 mmol/L
ANION GAP
<7 years: Not established
≥7 years: 7-15
BLOOD UREA NITROGEN
Males:
<12 months: Not established
1-17 years: 7-20 mg/dL
≥18 years: 8-24 mg/dL
Females:
<12 months: Not established
1-17 years: 7-20 mg/dL
≥18 years: 6-21 mg/dL
CREATININE
Males:
0-11 months: 0.17-0.42 mg/dL
1-5 years: 0.19-0.49 mg/dL
6-10 years: 0.26-0.61 mg/dL
11-14 years: 0.35-0.86 mg/dL
≥15 years: 0.74-1.35 mg/dL
Females:
0-11 months: 0.17-0.42 mg/dL
1-5 years: 0.19-0.49 mg/dL
6-10 years: 0.26-0.61 mg/dL
11-15 years: 0.35-0.86 mg/dL
≥16 years: 0.59-1.04 mg/dL
ESTIMATED GLOMERULAR FILTRATION RATE (eGFR)
≥ 18 years old: ≥60 mL/min/BSA (body surface area)
Estimated GFR calculated using the 2021 CKD-EPI creatinine equation
Note: eGFR results will not be calculated for patients younger than 18 years old.
CALCIUM
<1 year: 8.7-11.0 mg/dL
1-17 years: 9.3-10.6 mg/dL
18-59 years: 8.6-10.0 mg/dL
60-90 years: 8.8-10.2 mg/dL
>90 years: 8.2-9.6 mg/dL
GLUCOSE
0-11 months: Not established
≥1 year: 70-140 mg/dL
Interpretation
Basic metabolic panel results are usually evaluated in conjunction with each other for patterns of results. A single abnormal test result could be indicative of something different than if more than 1 of the test results are abnormal. Many conditions will cause abnormal results including kidney failure, breathing problems, and diabetes-related complications.
Cautions
No significant cautionary statements
Method Description
Sodium, Potassium, Chloride:
The ion selective electron (ISE) module indirectly measures the electromotive force (EMF) difference between an ISE and a reference electrode. The EMF of the ISE is dependent on the ion concentration of the sample. The EMF of the reference electrode is constant. An electronic calculation circuit converts EMF of the sample to the ion concentration of the sample.(Package insert: ISE Indirect Na, K, CL: for Gen 2. Roche Diagnostics; 12/2020)
Bicarbonate:
This is a photometric rate reaction. Bicarbonate (HCO3[-]) reacts with phosphoenolpyruvate in the presence of phosphoenolpyruvate carboxylase to produce oxaloacetate and phosphate. The oxaloacetate produced is coupled with reduced nicotinamide adenine dinucleotide (NADH) in the presence of malate dehydrogenase to produce malate and NAD(+). The consumption of NADH causes a decrease in absorbance and is monitored in the ultraviolet range of 320 to 400 nm. The rate of change is directly proportional to the concentration of bicarbonate.(Package insert: Bicarbonate reagent. Roche Diagnostics; 04/2019)
Anion Gap:
This is a calculated result. The following equation is used to calculate the anion gap (A gap):
A gap =Na - (Cl + HCO3[-])
Blood Urea Nitrogen:
This is a kinetic UV assay where urease cleaves urea to form ammonia and carbon dioxide. The ammonia formed then reacts with alpha-ketoglutarate and NADH in the presence of urease/glutamate dehydrogenase to yield glutamate and NAD(+). The decrease in absorbance, due to the consumption of NADH, is measured kinetically and is proportional to the amount of urea in the sample.(Package insert: Urea/BUN reagent. Roche Diagnostics; 12/2019)
Creatinine:
This enzymatic method is based on the conversion of creatinine with the aid of creatininase, creatinase, and sarcosine oxidase to glycine, formaldehyde, and hydrogen peroxide. Catalyzed by peroxidase the liberated hydrogen peroxide reacts with 4-aminophenazone and HTIB (hydroxy[tosyloxy]iodobenzene) to form a quinone imine chromogen. The color intensity of the quinone imine chromogen formed is directly proportional to the creatinine concentration in the reaction mixture.(Package insert: Creatinine Plus ver.2. Roche Diagnostics; 02/2019)
Calcium:
Calcium ions react with NM-BAPTA (5-nitro-5'-methyl-1,2-bis[o-aminophenoxy]ethane-N,N,N',N'-tetraacetic acid) under alkaline conditions to form a complex. This complex reacts in the second step with EDTA. The change in absorbance is directly proportional to the calcium concentration and is measured photometrically.(Package insert: Calcium Gen.2 reagent, Roche Diagnostics; 07/2019)
Glucose:
Glucose in the sample, in the presence of hexokinase, is converted to glucose-6-phosphate (G6P). In the presence of nicotinamide adenine dinucleotide phosphate (NADP[+]), glucose-6-phosphate dehydrogenase oxides G6P to gluconate-6-phosphate and NADPH. The rate of NADPH formation is directly proportional to glucose concentration in the sample and is measured photometrically.(Package insert: Glucose Gen.3 Reagent. Roche Diagnostics; 11/2021)
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
84132
84295
82435
82374
84520
82565
82310
82947
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| BMAMA | Basic Metabolic Panel, S | 24321-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AGAP | Anion Gap | 33037-3 |
| BUN | Bld Urea Nitrog (BUN), S | 3094-0 |
| CL | Chloride, S | 2075-0 |
| GLURA | Glucose, Random, S | 2345-7 |
| HCO3 | Bicarbonate, S | 1963-8 |
| CA | Calcium, Total, S | 17861-6 |
| NAS | Sodium, S | 2951-2 |
| KS | Potassium, S | 2823-3 |
| CRTSA | Creatinine, S | 2160-0 |
| EGFR1 | Estimated GFR (eGFR) | 98979-8 |