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Test Code CTFNA Cytology Fine-Needle Aspiration, Varies


Ordering Guidance


If a consultation is desired, order PATHC / Pathology Consultation.



Necessary Information


1. An acceptable cytology request form must accompany specimen containers and include the following: Patient's name, medical record number, date of birth, sex, source (exact location and procedure used), date specimen was taken, name of ordering physician and pager number.

2. Submit any pertinent history or clinical information.



Specimen Required


Specimen Type: Slide

Container/Tube: Plastic slide container

Specimen Volume: Smear

Collection Instructions:

1. Smears should be immediately fixed in 95% ethanol or sprayed with commercially available fixative. Smears that have been air-dried or Diff-Quik stained may also be accepted.

2. Label containers with a minimum of 2 unique identifiers (eg, patient name and medical record number or date of birth), specimen source, and date of collection. Label each glass slide in pencil with a minimum of 2 unique identifiers. If multiple slides are submitted, each slide must have proper identification.

 

Specimen Type: Fluid

Container/Tube: 60-mL (2 oz) jar with screw cap, 50-mL disposable centrifuge tube with screw cap, or 15-mL test tube with screw cap

Specimen Volume: Any amount

Collection Instructions:

1. Preferred method is no fixative added to fluid prior to processing and the specimen must be received and processed by the Cytology Laboratory within 1 hour of collection.

2. If not possible to submit within 1 hour, specimen should be refrigerated no longer than 62 hours. Additional acceptable fixatives are specimens with equal volume of 50%, 70%, 80%, or 95% ethanol, PreservCyt solution, CytoRich Red, or CytoLyt.

3. Label containers with a minimum of 2 unique identifiers (eg, patient name and medical record number or date of birth), specimen source, and date of collection.

 

Specimen Type: Tissue

Container/Tube: 50-mL disposable centrifuge tube with screw cap or 60-mL (2 oz) jar with screw cap containing 10% neutral-buffered formalin

Specimen Volume: Any amount

Collection Instructions:

1. Tissue fragments must be submitted in 10% neutral-buffered formalin.

2. Label containers with a minimum of 2 unique identifiers (eg, patient name and medical record number or date of birth), specimen source, and date of collection.


Useful For

Detection of malignancy

 

Detection of certain inflammatory conditions

Testing Algorithm

If an additional specimen is submitted along with the slides, then a cell block will be made at an additional charge.

 

Includes testing from virtually any body site that can be aspirated with a fine-needle (22-gauge or smaller).

Method Name

Light Microscopy

Reporting Name

Cytology Fine Needle Aspiration

Specimen Type

Varies

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Refrigerated 

Reject Due To

No specimen should be rejected.

Clinical Information

Aspiration cytology from a variety of organ sites is useful in the determination of pathologic states, particularly neoplasms. Commonly examined sites include lung, liver, lymph nodes, pancreas, kidney, thyroid, retroperitoneum, breast, salivary glands, and soft tissue. In many cases, an open biopsy is no longer required to make a diagnosis.

Reference Values

Negative for malignant cells

Interpretation

Aspiration therapy is highly specific with rare false-positives. A positive diagnosis should be definitive for malignancy.

 

Precise cell typing is variably possible depending on circumstances.

Cautions

Nondiagnostic results are issued when material is inadequate for a diagnostic impression.

 

A negative result must not be taken as definitive in the face of strong clinical suspicion. If the diagnosis is less than definitive (ie, suspicious), a follow-up biopsy may be recommended.

 

This test is not useful for most inflammatory conditions such as hepatitis, glomerulonephritis, etc. However, it may be helpful in obtaining material for culture and in identifying positive organisms in infectious diseases.

 

Slides must be fixed promptly after smearing to ensure adequate evaluation.

Method Description

Slides are stained by a modified Papanicolaou method and examined microscopically. DiffQuik stains may be used on air-dried specimens. On rare occasions, immunostains may be used secondarily as appropriate.(Unpublished Mayo method)

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

88173

88305-CBKPC (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CTFNA Cytology Fine Needle Aspiration 33718-8

 

Result ID Test Result Name Result LOINC Value
71690 Interpretation 59465-5
71691 Participated in the Interpretation No LOINC Needed
71689 Report electronically signed by 19139-5
71274 Addendum 35265-8
71275 Gross Description 22634-0
71644 Adequacy Evaluation 11552-7
CY067 Collection Procedure 33724-6
CY054 Source 22633-2
CY055 Clinical History 22636-5
CY056 Fixative 8100-0
71566 Disclaimer 62364-5
71812 Case Number 80398-1